PrEP (Pre-Exposure Prophylaxis)

PrEPX-SA South Australian PrEP Trial


PrEPX-SA will monitor how providing large-scale access to Pre-Exposure Prophylaxis (PrEP) medication impacts the rate of new infections across the state. There will be 500 places available in the study.


SA Health, SAHMRI and the Alfred have partnered together to deliver PrEPX-SA the South Australian PrEP trial, modelled on the PrEPX study in Victoria.


This clinical trial will be delivered through 57 Hyde Street (SAMESH), Clinic 275 and O'Brien street but will also include select regional clinics.


To learn more about the trial please visit the Alfred's PrEPX-SA trial information page.


The trial is now open and you can sign up here - Register for PrEPX-SA


  • What is PrEP?

    PrEP is a medical HIV prevention method where people who are HIV negative take medication to reduce their risk of contracting HIV.1 The medication most commonly used in PrEP and PrEP trials around the world is Truvada®, a pill that contains a combination of two antiretroviral medicines: tenofovir and emtricitabine. Truvada® is also one of a number of medications used to suppress the virus in people living with HIV.


    Several clinical trials such as the Proud study, have shown PrEP to be extremely effective in preventing HIV infection.2 Along with other prevention methods like condoms, PrEP can offer protection against HIV if taken as prescribed.


    PrEP is not available in Australia at a subsidised price through the Pharmaceutical Benefits Scheme (PBS), but can currently be obtained with:


    • A private script from a doctor to import a 3 month supply of Truvada┬« for individual use, costing approximately $10,000 per year
    • A private script from a doctor to import a 3 month supply of a generic form of PrEP for individual use, costing approximately $1,300
    • Participation in a clinical PrEP trial


    Currently PrEP is not part of the PBS, while SAMESH will continue to focus on raising awareness of existing HIV-prevention strategies, like condoms, PEP (Post-Exposure Prophylaxis), and treatment as prevention, moving forward SAMESH will be responsive to the national and community dialogue surrounding the need for PrEP.


    If you would like to know more about PrEP you can check our Fact Sheet.


    SAMESH has put forward a Position Statement explaining its stance on PrEP which can be read here.


    1 M Grant, et al, Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study, Lancet Infectious Diseases 2014, Vol 14:820-29


    2 C Hankins, et al, Translating PrEP effectiveness into public health impact: key considerations for decision-makers on cost-effectiveness, price, regulatory issues, distributive justice and advocacy access, Journal of the International AIDS Society 2015, Vol 18 (Supp 3):19973, pg. 3.

  • PrEP SA! Community forum

    PrEPX-SA Community Forum

    April 2017 SAMESH held a community forum with the lead investigators of the South Australian PrEP forum,

    Panelists: Australian Leatherman Gary Ebert, Dr Charlotte Bell, Prof Steve Wesslingh, Prof Edwina Wright

    In 2015 SAMESH and the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM) brought leading HIV clinicians and experts on HIV PrEP, from South Australia & Victoria  together for a community discussion on PrEP and HIV prevention in the south Australian landscape.



    Associate Professor Edwina Wright

    Alfred Hospital, Burnet Institute

    & Chief Investigator for VicPrEP

    Demonstration Project



    Associate Professor Levinia Crooks

    Chief Executive Officer



    Dr Charlotte Bell

    Sexual Health Physician

    Clinic 275, North Terrace, Adelaide


    Wills Logue

    Team Leader, SAMESH, Adelaide


    Survey Results

    Attendees to the community forum were surveyed before and after the forum in order to gauge community knowledge and opinion, the results of which are available here.


    Pre-forum survey results


    Post-forum survey results